Indian Journal of Community Medicine

ORIGINAL ARTICLE
Year
: 2020  |  Volume : 45  |  Issue : 4  |  Page : 399--404

Prevalence of Vitamin B12 deficiency and its associated risk factors among pregnant women of rural South India: A community-based cross-sectional study


Anitha Mohanraj Barney1, Vinod Joseph Abraham2, Sumita Danda4, Anne George Cherian3, S Vanitha4 
1 Department of Community Health; Department of Clinical Genetics, Christian Medical College, Vellore, Tamil Nadu, India
2 Department of Community Health, Christian Medical College, Vellore, Tamil Nadu, India
3 Department of Community Health; Department of Obstetrics and Gynecology, Christian Medical College, Vellore, Tamil Nadu, India
4 Department of Clinical Biochemistry, Christian Medical College, Vellore, Tamil Nadu, India

Correspondence Address:
Ms. Anitha Mohanraj Barney
Department of Clinical Genetics, Christian Medical College, Vellore - 632 004, Tamil Nadu
India

Introduction: Vitamin B12 is essential for the normal functioning of the nervous system and for the formation of red blood cells. Vegetarian diet, low socioeconomic status, and social and religious reasons are known risk factors of its deficiency. Pregnant women, children, and the elderly are vulnerable groups. Indians have the highest prevalence, but the data among pregnant women in the rural setting is lacking. Objectives: The objective of this study is to assess the prevalence of Vitamin B12 deficiency and its associated factors among pregnant women of rural South India. Materials and Methods: A cross-sectional study was conducted to recruit consecutive 120 multigravida women with ≤20 weeks of gestation, attending the mobile doctor run clinic of Kaniyambadi block, Vellore. A structured questionnaire was administered, and blood samples were collected. Results: The prevalence of Vitamin B12 deficiency (<200 pgm/ml) and anemia (Hb ≤10.5 g/dL) was 55% and 17.5%, respectively. Only 11.7% were B12 deficient and anemic. Past history of abortion (odds ratio [OR] = 0.5), fatigue (OR = 0.4), and low B12 intake (OR = 2) was associated only in the bivariate analysis. First trimester (OR = 3.9) and obesity (OR = 9.6) were found to be independent risk factors of Vitamin B12 deficiency. Conclusion: Our study showed a high prevalence of Vitamin B12 deficiency in pregnancy in rural India. Some risk factors were identified. However, studies with a higher sample size will be beneficial to study the associated risk factors better.


How to cite this article:
Barney AM, Abraham VJ, Danda S, Cherian AG, Vanitha S. Prevalence of Vitamin B12 deficiency and its associated risk factors among pregnant women of rural South India: A community-based cross-sectional study.Indian J Community Med 2020;45:399-404


How to cite this URL:
Barney AM, Abraham VJ, Danda S, Cherian AG, Vanitha S. Prevalence of Vitamin B12 deficiency and its associated risk factors among pregnant women of rural South India: A community-based cross-sectional study. Indian J Community Med [serial online] 2020 [cited 2020 Nov 25 ];45:399-404
Available from: https://www.ijcm.org.in/article.asp?issn=0970-0218;year=2020;volume=45;issue=4;spage=399;epage=404;aulast=Barney;type=0