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ORIGINAL ARTICLE  
Year : 2020  |  Volume : 45  |  Issue : 4  |  Page : 454-457
 

Impact of community defluoridation on a village endemic for hydric fluorosis in rural Karnataka, India


1 Department of Community Medicine, MS Ramaiah Medical College, Bengaluru, Karnataka, India
2 Department of Biostatistics, MS Ramaiah Medical College, Bengaluru, Karnataka, India

Date of Submission29-Nov-2019
Date of Acceptance25-Jun-2020
Date of Web Publication28-Oct-2020

Correspondence Address:
Dr. Arjunan Isaac
Department of Community Medicine, MS Ramaiah Medical College, Bengaluru, Karnataka
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/ijcm.IJCM_489_19

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   Abstract 


Introduction: Excessive intake of fluorides can lead to the development of fluorosis, a serious public health issue in India. The objective of this study was to assess the impact of community defluoridation in preventing fluorosis in Kaiwara village. Methodology: This community interventional trial was conducted in Kaiwara village, Karnataka, after obtaining ethical clearance. The study included 903 participants; preintervention data were collected by recording the required parameters. The postinterventional study was carried out 2 years after installing the reverse osmosis plant. Data from pre- and post-intervention study were compared. Results: Dean's index showed no significant change in the pre- and post-intervention period for its various categories (P = 0.543). However, the mean urine fluoride levels were found to be decreased significantly (Wilcoxon Signed-Rank test, P < 0.001). Conclusion: This study demonstrates the importance of providing defluorinated water to the village population as a potential solution for fluorosis.


Keywords: Community health services, fluorides, fluorosis, public health, reverse osmosis


How to cite this article:
Isaac A, Pruthvish S, Haridas R, Murthy N S. Impact of community defluoridation on a village endemic for hydric fluorosis in rural Karnataka, India. Indian J Community Med 2020;45:454-7

How to cite this URL:
Isaac A, Pruthvish S, Haridas R, Murthy N S. Impact of community defluoridation on a village endemic for hydric fluorosis in rural Karnataka, India. Indian J Community Med [serial online] 2020 [cited 2020 Dec 1];45:454-7. Available from: https://www.ijcm.org.in/text.asp?2020/45/4/454/299436





   Introduction Top


Fluorosis is an endemic disease that has affected 70 million individuals and is prevalent in 22 states of India, particularly in parched parts of the country.[1] The process of removal of harmful fluoride from water is called defluoridation.[2] The world's ground fluoride stores are estimated to be 85 million tons, of which almost 12 million tons are in India.[3] As Kaiwara, a part of Chikkaballapur district, Karnataka, has no alternate source of water, it is dependent solely on groundwater through bore wells for its water supply.[4]

Advanced defluoridation procedures have commenced in India. Nalgonda technique is one of them, which utilizes alum and lime combination in a two-step process. The process has disadvantages like the undesirable taste of treated water, high-cost maintenance, temperature, and the presence of silicate ions.[5] Reverse osmosis (RO) established by Jean-Antoine Nollet in 1748 is presently the most effective method in terms of fluoride removal.[6]

In a study conducted by Arvind et al. in Kaiwara and the villages under Kaiwara Primary Health Center, it was found that of the 1544 children examined, 42.1% and 8.4% had dental fluorosis and genu valgum, respectively,[4] which clearly proved increased consumption of fluoride. This study is aimed to assess the impact of community defluoridation in Kaiwara, a village endemic for hydric fluorosis.


   Methodology Top


This was a community intervention trial carried out at Kaiwara village, Chikkaballapur district, Karnataka, from January 2011 to December 2014. After obtaining ethical clearance, a preliminary count and numbering of houses were done. A baseline study survey was performed in 3003 participants who aged ≥3 years and were permanent residents of Kaiwara village. The flow chart for subject enrollment and post-intervention analysis is presented in [Figure 1]. Demographic details such as age, education, and occupation were collected from the head of the family using the direct interview method and recorded in the pretested structured protocol. Signs of fluorosis were collected by using the illustration chart published by Susheela.[7] Detection of dental fluorosis was done using the Dean's Index (Fluorosis Index). Genu valgum was measured with the help of a divider and a plastic scale by measuring the distance between the medial malleoli at the ankle when the subject stands or lies down with the knees touching each other, and was accordingly graded as mild (<5 cm), moderate (5–10 cm) and severe (>10 cm). Levels of fluoride in drinking water were recorded using ion chromatography. Iodine deficiency disorder was identified by clinical examination using the WHO criteria. One hundred participants were randomly enrolled for the preintervention study (urine analysis). These tests were piloted and used as a part of the protocol.
Figure 1: Participants in various stages of the community intervention trial

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After the preintervention study, details about infrastructure available (electricity, water supply, workforce) were collected, and considering the cost, the community was willing to afford, the RO plant was installed. The Council for Scientific and Industrial Research, Government of India, offered a 40,000 L capacity custom made RO unit for community defluoridation to pilot in the village. The Kaiwara Gram Panchayath granted land for the installation of the RO plant. The money collected by selling the processed water was used to run and maintain the RO plant. The cost of Rs 5/-per household was calculated considering Rs 3/-towards electricity and water charges for running of the RO Plant, maintenance charges for the RO plant (filter replacement, pump repair, etc.,) and salaries for the watchman, plant operator, and electrician. Rs 2/-was further collected towards payment for the water distribution vehicle maintenance and petrol for the running of the vehicle as well as salary for the water distributer. This processed water was supplied to all the subjects as drinking water and for cooking purpose.

Every 6 months, the fluoride level of the processed water was assessed by the ion analyzer. After 2 years, postintervention study was carried out on 250 households that included 1038 subjects who regularly used the processed water and were available for examination. The same parameters of the pre-intervention study were applied. Of the 1038 subjects available, 903 participants who matched by names, address, and age with the pre- and post-intervention analysis were considered for comparison. Out of 903 participants, 101 participants were randomly enrolled for the postintervention urine analysis and matched for age and sex with the pre-intervention study participants. Urine fluoride levels were estimated using an ELICO-LI-126 fluoride ion analyzer.


   Results Top


It was observed that among 903 participants compared, 60.5% of the study participants in the preintervention and 60.6% in the postintervention remained normal, whereas 17.9% of study participants in the preintervention and 18% of participants in the postintervention showed signs of fluorosis. The difference in age and gender in the pre- and post-intervention groups was noted to be insignificant (P = 0.423: Female and 0.287: Male), as presented in [Table 1]. The Deans Index showed no significant change in the pre- and post-intervention among its various categories (P = 0.543), as shown in [Table 1].
Table 1: Characteristics of participants during pre- and post-intervention

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During preintervention, 2.2% of total of 903 participants could not touch their toes, whereas, in the postintervention, only 0.2% of participants could not touch their toes. This difference was found to be statistically significant (P < 0.001), as shown in [Table 1].

In the preintervention time, it was observed that 0% of subjects (males and females) were in the safety zone (<0.1 ppm); however, postintervention, 31.2% of females and 18.9% of male participants had entered the safety zone. Differences in urine fluoride levels in females between pre- and post-intervention were found to be statistically significant (P < 0.01). Urine fluoride levels were found to be high in the age group of 20–39 years, followed by 40–59 years [Table 2].
Table 2: Study population distribution analysis in pre- and post-intervention

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Before intervention, water samples were collected from four main tanks. The measures of all the components in each tank were noted, and the average was calculated, which was beyond the safety limit, 2.07 mg/l of fluoride. Postintervention, water samples were collected from the respective houses, and levels of fluoride were found to be within safety limits (<0.01), as shown in [Table 3].
Table 3: Complete chemical analysis of baseline water available at Kaiwara village before and after intervention

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   Discussion Top


Fluorine is the 13th most abundant element that is naturally introduced into the environment through water and air.[8] Increased levels of fluorine intake will cause dental and skeletal fluorosis, and reducing the levels of fluoride in drinking water (de-fluoridation) will prevent fluorosis.[9] In a study by Kumar et al.,[10] the severity of dental fluorosis was assessed by Dean's index and was considered as a gold standard; accordingly, in the present study, Deans index was used for assessing fluorosis. It was observed that 17.9% of study participants in the pre-intervention and 18% of participants in the postintervention showed signs of fluorosis, included in the very mild, mild, moderate, and severe forms of dental fluorosis. Dean's Index showed no significant change pre- and post-intervention among its various categories (P = 0.543). There was a statistically significant difference (P < 0.01) in the population that could not touch their toes pre- and post-intervention. Similar findings were seen with chin-to-chest and hands-behind-the-head test, but the results were not statistically significant. Susheela[7] in her book revealed that with sustained use of defluoridated water, rigidity, stiffness, and restricted movement in the backbone, knee, neck, and shoulder reduced gradually in fluorosis patients. Fluorosis was observed more in the age group of 20–39 years. It was noted that the majority of participants studied during preintervention had urine fluoride levels >0.5 ppm while the majority of participants studied in the postintervention had urine fluoride levels below 0.5 ppm.[11],[12],[13] Adult urinary fluoride levels determined by Toth et al. showed increased signs of fluorosis after the consumption of fluoridated milk.[14] A study done by Das and Mondal in West Bengal found a strong positive correlation between water fluoride levels and urinary fluoride levels (r = 0.513, P < 0.01) and similar results were seen in this study.[15] It was observed that in all age groups and in both genders, there was a statistically significant reduction in the urine fluoride levels before and after the intervention, similar to Chen et al.[16]

This study has a few limitations. First, one-to-one pre- and post-intervention comparison of urine fluoride levels was not done due to the unavailability of the same subjects in both the pre- and post-intervention stages. Second, pregnant women and babies may be included for future follow-up studies as change in DF can be expected only among children conceived and born in the postdefluoridation phase.


   Conclusion Top


This study demonstrates the importance of providing processed or de-fluoridated water to the population in endemic areas by setting up a sustainable community de-fluoridation RO plant, a potential solution for preventing hydric fluorosis.

Financial support and sponsorship

Nil.

Conflicts of interest

There are no conflicts of interest.



 
   References Top

1.
Annadurai ST, Rengasamy JK, Sundaram R, Munusamy AP. Incidence and effects of fluoride in Indian natural ecosystem: A review. Adv Appl Sci Res 2014;5:173-85.  Back to cited text no. 1
    
2.
Taricska JR, Lawrence K, Hung YT, Li KH. Fluoridation and defluoridation. In: Advanced Physicochemical Treatment Processes. Handbook of Environmental Engineering. Vol 4. Totowa, NJ: Humana Press. 2006; p. 293-315.  Back to cited text no. 2
    
3.
Teotia SP, Teotia M, Singh KP. Highlights of forty years of research on endemic skeletal fluorosis in India. In: 4th International Workshop on Fluorosis Prevention and Defluoridation of Water. ISFR, EnDeCo, ICOH. 2004; p. 107-25.  Back to cited text no. 3
    
4.
Arvind BA, Isaac A, Murthy NS, Shivaraj NS, Suryanarayana SP, Pruthvish S. Prevalence and severity of dental fluorosis and genu valgum among school children in rural field practice area of a medical college. Asian Pacific Journal of Tropical Disease 2012;2:465-9.  Back to cited text no. 4
    
5.
Meenakshi, Maheshwari RC. Fluoride in drinking water and its removal. J Hazard Mater 2006;137:456-63. doi:10.1016/j.jhazmat.2006.02.024.  Back to cited text no. 5
    
6.
Bose S, Yashoda R, Puranik MP. Novel materials for defluoridation in India: A systematic review. J Dent Res Rev 2019;6:3-8.  Back to cited text no. 6
  [Full text]  
7.
Susheela AK. Treatise on fluorosis. Fluor Res Rural Develop Found 2001;34:181-3.  Back to cited text no. 7
    
8.
CDC, Using Fluoride to Prevent and Control Dental Caries in the United States, Oral Health Resource-Resource Library, Fact Sheet, Centers for Disease Control and Prevention, US Department of Health and Human Services; 07 August, 2002.  Back to cited text no. 8
    
9.
CDC, Engineering and Administrative Recommendations for Water Fluoridation, MMWR Recommendation and Reports, Centers for Disease Control and Prevention. Vol. 44. US Department of Health and Human Services; 1995. p. 13.  Back to cited text no. 9
    
10.
Kumar N, Gauba K, Goyal A, Kapur A. Comparative evaluation of three different recording criteria of dental fluorosis in a known endemic fluoride area of Haryana. Indian J Med Res 2018;147:567-72.  Back to cited text no. 10
[PUBMED]  [Full text]  
11.
Singh B, Gaur S, Garg VK. Fluoride in drinking water and human urine in Southern Haryana, India. J Hazard Mater 2007;144:147-51.  Back to cited text no. 11
    
12.
Jarquín-Yañez L, de Jesús Mejía-Saavedra J, Molina-Frechero N, Gaona E, Rocha-Amador DO, López-Guzmán OD, et al. Association between urine fluoride and dental fluorosis as a toxicity factor in a rural community in the state of San Luis Potosi. ScientificWorldJournal 2015;2015:647184.  Back to cited text no. 12
    
13.
Villa A, Anabalón M, Cabezas L. The fractional urinary fluoride excretion in young children under stable fluoride intake conditions. Community Dent Oral Epidemiol 2000;28:344-55.  Back to cited text no. 13
    
14.
Toth Z, Ginter Z, Banoczy J. The effect of ingested fluoride administered in salt, milk, and tablets on salivary and urinary fluoride concentrations. Fluoride 2005;38:199-204.  Back to cited text no. 14
    
15.
Das K, Mondal NK. Dental fluorosis and urinary fluoride concentration as a reflection of fluoride exposure and its impact on IQ level and BMI of children of Laxmisagar, Simlapal Block of Bankura District, W.B., India. Environ Monit Assess 2016;188:218.  Back to cited text no. 15
    
16.
Chen S, Li B, Lin S, Huang Y, Zhao X, Zhang M, et al. Change of urinary fluoride and bone metabolism indicators in the endemic fluorosis areas of southern China after supplying low fluoride public water. BMC Public Health 2013;13:156.  Back to cited text no. 16
    


    Figures

  [Figure 1]
 
 
    Tables

  [Table 1], [Table 2], [Table 3]



 

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